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Search Results for " 3cl pro "

Targets

9

Compounds

3

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T60095 CCF0058981 SARS-CoV
CCF0058981 (CCF981) is a 3-chlorophenyl analogue, serving as a noncovalent inhibitor of SARS-CoV-2 3CL pro (SC2), demonstrating potent activity with an IC50 of 68 nM. It also exhibits inhibitory effects against SARS-CoV-...
T9574 PF-07304814 Lufotrelvir
Lufotrelvir (PF-07304814) is a phosphate prodrug of PF-00835231 which acts as a potent 3CL pro protease ( M pro ) inhibitor with SARS-CoV-2 antiviral activity. Lufotrelvir binds and inhibits SARS-CoV-2 3CL pro activity w...
T40320 Antiviral agent 5
Antiviral agent 5 is a crucial intermediate utilized in the development of antiviral agents that specifically target 3C and 3CL proteases, which includes the SARS-CoV-2 M pro enzyme.
T79676 SARS-CoV-2 3CLpro-IN-21 Virus Protease
SARS-CoV-2 3CLpro-IN-21 (Compound D6) is an irreversible, covalent inhibitor of SARS-CoV-2 3CL pro, demonstrating potent inhibition with an IC50 of 0.03 μM. Additionally, it exhibits inhibitory activity against SARS-CoV-...
T75065 Antiviral agent 25
Antiviral agent 25 (compound 6g), a novel non-peptide analog covalent inhibitor of SARS-CoV-2 3CL pro, exhibits robust inhibitory activity against both SARS-CoV-2 3CL pro and SARS-CoV-2 PL pro, with IC50 values of 0.118 ...
T63537 SARS-CoV-2 3CLpro-IN-1
SARS-CoV-2 3CLpro-IN-1 (Compound 14c) is a highly potent inhibitor specifically designed to target and inhibit the activity of SARS-CoV-2 3CL pro, which is a cysteine-protease found in the main coronaviruses. This partic...
T75241 Ledipasvir hydrochloride GS-5885 hydrochloride
Ledipasvir hydrochloride (GS-5885) is a hepatitis C virus NS5A inhibitor, displaying potent activity with EC50 values of 34 pM for genotype 1a replicon and 4 pM for genotype 1b replicon. Additionally, it acts as a SARS-C...
T78119 Z-L(D-Val)G-CHN2 HSV
Z-L(D-Val)G-CHN2, an isoform of Z-LVG-CHN2, serves as a cell-permeable and irreversible inhibitor of cysteine proteinase. This tripeptide derivative emulates a segment of the human cysteine proteinase-binding center and ...
T73898 Paritaprevir dihydrate
Paritaprevir dihydrate (ABT-450), a highly effective and orally administered antiviral, acts as a non-structural protein 3/4A (NS3/4A) protease inhibitor, displaying EC50 values of 1 and 0.21 nM against HCV genotypes 1a ...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPK-01348 3CLpro/3C-like Protease Protein, SARS-COV-2, Recombinant (aa 1-306) SARS-CoV-2 E. coli
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al...
TMPJ-01449 3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant SARS-CoV-2 E. coli
The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precur...
TMPJ-01448 3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant (His) 2019-nCoV E. coli
The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precur...
TargetMol